My PhD research focuses on using existing data to optimise adaptive interventions in chronic diseases. I’m particularly interested in learning how routine data might aid in designing a clinical trial of personalised treatment sequences for epilepsy. I plan to use a novel Sequential Multiple-Assignment Randomised Trial (SMART) design. I intend to generate evidence on effective treatment regimens for epilepsy patients based on their individual patient features and treatment responses. As a result, I will address the treatment conundrum in one-third of patients diagnosed with epilepsy and started on antiepileptic drugs but do not achieve seizure remission.
Education: MSc in Epidemiology from the London School of Hygiene and Tropical Medicine, Postgraduate Diploma in Health Research Methods, and BSc in Nursing. Trained in Advanced Clinical Research Associate Certification, Advanced Clinical ICH GCP Certification, and Pandemic Emergence, Spread, and Response.
Research experience: His experience includes seizure, epilepsy aetiology classification, and epilepsy diagnosis in Kenya, as well as the implementation of mental and epilepsy awareness campaigns, assessing the long-term impact of malaria prevention interventions on neurodevelopmental outcomes and schooling among Kenyan children, psychometric assessments, and estimating the relationship between anthropometric measures and iron deficiency and anaemia among East African children.
LinkedIn: https://www.linkedin.com/in/isaac-egesa-648261133/
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